I shared the story of dropping my mother and father to early onset dementia in final week’s publication (hyperlink in case you missed it) and I used to be blown away by the response. Tons of of you wrote again. Many shared your personal tales of watching family members endure by means of dementia, most cancers, or power illness.
In order that’s what at this time is about.
I’m sharing my private longevity must-haves. What makes it vital? It signifies that whether or not I’m touring, buried in work, or even when I’m sick, this stuff don’t get dropped. They’re the practices that I consider transfer the needle probably the most for dwelling not solely longer, however higher.
They’re not meant to be prescriptive—these are merely the practices I’ve landed on after 41 years in dentistry.
Listed below are my 13 must-haves for longevity:
1. Spermidine
Autophagy—the physique’s pure “mobile cleanup” course of—is the lever for longevity. Spermidine is among the best-studied pure compounds for kickstarting autophagy. It clears out broken proteins (assume amyloid plaques within the mind). It improves mitochondrial operate. It’s correlated with decrease all-cause mortality. That is the one I take.
2. C15: 0
C15:0 is a hint fatty acid present in full-fat dairy and a few fish, and it’s starting to be acknowledged as a vital fatty acid for mobile well being—very similar to omega-3s had been a number of many years in the past.
Right here’s why I take it every day:
- It strengthens cell membranes, particularly in getting older cells which can be extra susceptible to break.
- It helps mitochondrial operate and reduces systemic irritation.
- It’s been proven to activate AMPK and PPAR pathways—which implies higher metabolic well being, decrease CRP, and enhanced mobile restore.
The science is early however compelling, and the security profile is clear. It’s one of many few dietary supplements I’ve seen with direct advantages throughout longevity, irritation, metabolic resilience, and temper.
Plus, it’s vegan—so when you keep away from dairy, you’re not lacking out on this vital nutrient. That is the one I take on daily basis.
3. Flossing (Each Evening)
Scientists have discovered gum illness micro organism (Porphyromonas gingivalis, specifically) within the brains of Alzheimer’s sufferers.
In a landmark 2019 examine, researchers didn’t simply present correlation—they proposed a causal mechanism: the micro organism migrate from infected gums into the bloodstream, cross the blood–mind barrier, and launch toxins that harm neurons.
Flossing is the most cost effective, quickest “neuroprotective” behavior you’ll ever do.
For those who don’t take away the micro organism from between your tooth, they’ll discover their approach into your mind. And neurologists and cardiologists are actually saying the identical factor. I predict this will likely be mainstream inside a decade.
4. Treating sleep prefer it’s my full-time job
You possibly can’t out-supplement unhealthy sleep. And mouth respiration, loud night breathing, and sleep-disordered respiration silently torch your mind and cardiovascular system. Sleep is the place the physique heals and the mind detoxes by means of the glymphatic system. Miss this, and nothing else issues.
I put on an oral equipment known as a mandibular development gadget, which maintains my airway and takes my AHI (respiration interruptions per hour) to almost zero. I tape my mouth shut at evening. I observe my sleep obsessively with an Oura ring.
5. Every day Morning Daylight
Ten minutes exterior—eyes uncovered to actual mild—units my circadian rhythm, boosts nitric oxide manufacturing.
If I’m touring, I’ll stroll exterior the lodge very first thing, even when it’s cloudy.
6. Power Coaching (2–3x per week)
Longevity is muscle-centric. Sarcopenia (age-related muscle loss) predicts falls, frailty, and early dying higher than ldl cholesterol ever will.
I don’t prepare for large biceps—I prepare so I can decide up my grandkids and hold climbing stairs in my 90s. That was the angle shift that helped me get into the gymnasium.
7. Oral & Intestine Microbiome Care
I keep away from alcohol-based mouthwash like poison—it wipes out the nice bugs that defend your coronary heart and mind. As an alternative:
- I take advantage of this prebiotic nano-hydroxyapatite toothpaste.
- I oil pull for two minutes.
- I take oral probiotics.
- I eat prebiotic meals like onion, artichokes, garlic, leeks ( bizarre quirk of mine is I don’t like bananas—however these are an excellent prebiotic meals as nicely)
Your mouth microbiome is your physique’s entrance line. Defend it.
8. Polyphenol-Wealthy Eating regimen (Olive Oil, Berries, Darkish Chocolate, Inexperienced Tea)
Polyphenols aren’t simply antioxidants—they sign your genes towards resilience.
My non-negotiables are inexperienced tea and additional virgin olive oil each single day. And sure, I journey with each of those! These little inexperienced tea packets make it simple to convey tea with me after I’m on-the-go.
9. Strolling (Particularly After Meals)
This has turn into a sacred ritual in my day. After dinner—irrespective of how lengthy the to-do record or how tempting the sofa—my spouse and I am going for a stroll. (It’s additionally an exquisite ritual for our marriage.)
Motion after meals blunts glucose spikes, improves insulin sensitivity, and helps digestion. It’s a easy however highly effective instrument for metabolic well being and longevity.
It additionally alerts to my physique that the day is winding down, helps me sleep higher, and provides me an opportunity to attach—whether or not that’s with my spouse, a podcast, or simply my very own ideas.
Even simply 10–quarter-hour makes a distinction. No particular gear and no gymnasium required!
10. Magnesium (Every day)
Practically 70% of individuals are poor. Magnesium calms the nervous system, regulates blood strain, helps deep sleep, and helps over 300 enzymatic reactions. I think about it foundational.
A typical mistake individuals make: don’t take only one sort—take a mix of a number of kinds of magnesium, like this onewhich I take every day.
11. Connection & Function
This one is one thing you’ll be able to’t get from a capsule or a tool. However the information is overwhelming: loneliness is as harmful as smoking 15 cigarettes a day. This is among the causes I’m right here, writing this article, working alongside my daughter and enterprise companion each at Ask the Dentist and at Fygg—it provides me connection and objective. I’ve at all times felt known as to the Latin root of the phrase physician which is “to show.” I discover objective in being a hands-on “on a regular basis” grandpa, and persevering with to be concerned as a father to my three grownup daughters of their 20s and 30s (parenting doesn’t cease at age 18!)
12. Understanding my fasting insulin rating
As a result of insulin resistance is the hearth behind almost each power illness—coronary heart illness, dementia, most cancers, even gum illness. And fasting insulin provides you an early warning, lengthy earlier than your blood sugar goes haywire.
This take a look at is nearly by no means ordered in a regular check-up. Nevertheless it needs to be. It’s low cost, easy, and tells you in case your cells have gotten immune to insulin—years earlier than a diabetes prognosis.
13. Avoiding sugar (as a lot as humanly attainable)
This one’s the toughest—and I’m not excellent. However I’ve realized that sugar is a gradual, sneaky wrecking ball relating to each oral and systemic well being.
It feeds the unsuitable microbes in your mouth and intestine. It spikes insulin. It drives irritation. And it accelerates getting older on the mobile stage—out of your mind to your arteries to your enamel.
Sugar can be deeply emotional. It’s tied to consolation, stress reduction, and nostalgia. That’s why I don’t use shame-based language round it—however I do respect how highly effective it’s, and the way urgently we have to deal with it like a severe well being threat.
Right here’s how I make it manageable:
- I learn each label—sugar hides in locations like salad dressing and tomato sauce.
- I by no means drink something with sugar in it—together with espresso and tea.
- I don’t hold it in the home. I get my “candy”from brain-building blueberries as an alternative!
- I observe what I name the “24-hour rule”: if I’m craving one thing candy, I delay it a day. More often than not, the craving disappears.
For me, avoiding sugar isn’t nearly tooth—it’s about defending my mind, my coronary heart, and my power.
I didn’t construct this record in a single day. A few of these took years to undertake. Others I’ve needed to battle exhausting to maintain.
Hit reply and ship me your prime 3. I’d love to listen to what retains you going.
P.S. Discover how #2, #3, and #6 all tie collectively? The mind, the mouth, and sleep all share the identical inflammatory pathways.
