Friday, February 27, 2026

Stop Glycogen Depletion & End Sturdy

You’ve skilled for 16 weeks, logged a whole bunch of miles, and executed each exercise completely.

Then mile 20 hits, and your legs flip to cement whereas runners you handed 5 miles in the past glide by such as you’re standing nonetheless.

The irritating half? You’re not undertrained.

Analysis by Benjamin Rapoport at MIT discovered that over 40% of marathon runners expertise “hitting the wall,” with the commonest collapse level occurring round mile 21.

So, how do you forestall your self from changing into a part of this 40%?

Properly, that’s what I’m going that will help you with in as we speak’s e mail on the six particular, research-backed methods that forestall metabolic failure earlier than it begins.

Sadly, most runners solely uncover these methods after their first marathon catastrophe.

However you possibly can implement all six of those protocols in your present coaching block and rework your remaining 10K from survival mode into your strongest miles.

Right here’s precisely how you can do it.

Technique #1: Begin Fueling Early

The largest mistake runners make isn’t fueling too little…it’s beginning too late.

Your physique shops roughly 90-120 minutes value of glycogen at marathon depth, which suggests most runners begin approaching empty someplace between miles 16-20.

A computational examine printed in PLOS Computational Biology demonstrated that athletes operating at 80-95% VO2max hit glycogen depletion round mile 21, the precise distance the place most marathoners report “hitting the wall.”

Right here’s the issue: for those who wait till mile 10 to start out fueling, you’re already behind.

Glycogen depletion occurs steadily, and by the point you’re feeling the vitality crash, your shops are critically low and tough to replenish whereas operating.

The Analysis-Backed Resolution

Research on carbohydrate consumption timing present that starting gas consumption at 30-45 minutes into your run prevents the sudden vitality deficit that derails efficiency within the remaining 10K.

The bottom line is constant, early consumption reasonably than taking part in catch-up once you’re already depleted.

Goal 30-60 grams of carbohydrates per hour for any effort exceeding 90 minutes, delivered in small frequent doses of 8-15 grams each 15-20 minutes.

How one can Implement This in Coaching

Begin training early fueling on each run longer than 90 minutes, starting at mile 3-4.

Set a timer in your watch to beep each 20 minutes as a fueling reminder—don’t depend on feeling hungry, as a result of by the point you’re feeling depleted, you’re already behind.

Use your lengthy runs to experiment with completely different gas sources and timing protocols so race day execution is automated.

Follow taking gas with water solely, by no means with sports activities drinks, as combining concentrated carbohydrates will increase osmolality and raises the chance of GI misery.

The aim is to reach at mile 20 with glycogen shops nonetheless topped off reasonably than desperately attempting to refuel an empty tank whereas sustaining race tempo.

What This Appears Like on Race Day

Mile 3-4: First gel or chew (15g carbs) + water

Mile 6-7: Second gas serving (15g carbs) + water

Mile 9-10: Third gas serving (15g carbs) + water

Proceed this 20-minute protocol via mile 24

By mile 20, you’ve consumed roughly 120-150g of carbohydrates, sustaining glycogen availability for the ultimate 10K as an alternative of operating on empty.

This early, constant fueling protocol is why some runners detrimental break up marathons whereas others crater.

Technique #2: Shield Your Abdomen & Enhance absorption of gels

Sadly, even with excellent fueling timing, there’s one drawback most runners by no means handle: your abdomen’s skill to truly take in these 60-75 grams of carbohydrates per hour.

Throughout marathon-intensity operating, blood stream to your digestive system drops by 60-70%, basically shutting down your abdomen’s capability to course of gas.

This implies gels sit unabsorbed, both triggering GI disasters at mile 20 or leaving you with nothing within the tank once you want it most.

Enhance gel absorption

Fortunately, there may be one physiological resolution that addresses this on the mobile stage: particular probiotic strains that enhance your intestine’s capability to soak up carbohydrates throughout train.

Analysis printed within the American Journal of Physiology demonstrated that probiotic supplementation elevated carbohydrate utilization by 18%.

This important elevated occurred as a result of the probitoics enhanced exercise of SGLT1 glucose transporters, the proteins answerable for shuttling carbohydrates out of your intestines into your bloodstream.

Retailer extra glycogen

One other good thing about probiotics is that they will help you retailer extra glycogen within the liver and muscle tissues.

The precise probiotic pressure Bifidobacterium longum has been proven in research to extend glycogen storage capability by 33% within the liver and 41% in skeletal muscle

This further storage offers you considerably bigger gas reserves on race day.

Extra storage & higher absorption means much less GI points

A landmark examine by Pugh et al. discovered that 4 weeks of probiotic supplementation decreased GI signs throughout marathon operating by 73%.

This occurs as a result of probiotics strengthen the mobile seals between intestinal cells that break down throughout onerous operating, stopping endotoxin leakage that triggers nausea, cramping, and urgency.

Analysis demonstrates that runners with elevated endotoxin ranges are 4x extra more likely to expertise GI signs, and that the Bifidobacterium and Lactobacillus strains particularly scale back each the severity and frequency of those race-derailing points.

Sensible Implementation

In contrast to race-day fueling ways you possibly can implement instantly, probiotic advantages require 2-4 weeks of constant supplementation to determine intestine barrier integrity and enhance absorption capability.

This implies you possibly can’t begin probiotics the week earlier than your marathon and anticipate outcomes. You could combine them into your coaching block alongside your fueling apply.

That’s why I at all times advocate our companion, MAS Flushto runners this time of 12 months.

MAS Flush was particularly formulated with the research-backed strains and dosages proven to enhance marathon fueling, retailer extra glycogen, shield the intestine, and enhance digestion.

So far as I do know, they’re the one probiotic with precise dietician and physician evaluations.

Mixed with the early fueling protocol outlined in technique 1, probiotics be sure that your intestine is definitely geared up to soak up and make the most of the gels you are taking reasonably than letting them sit unprocessed in your abdomen.

Technique #3: Financial institution Power within the First Half

Right here’s the place most runners fail: they begin too quick as a result of they really feel too good.

The primary 5 miles of a marathon really feel deceptively simple, main runners to imagine they’ll maintain a sooner tempo than their coaching suggests.

Analysis printed in Frontiers in Physiology examined the physiology of detrimental splits and located that beginning conservatively…

  • Reduces early glycogen depletion
  • Reduces the buildup of lactate and hydrogen ions
  • Preserves muscular effectivity and delays central fatigue.

Sadly, the injury from aggressive early pacing compounds exponentially within the remaining 10K.

A examine on marathon pacing methods confirmed that conservative early pacing results in decrease perceived exertion within the first half, which rises linearly all through the race reasonably than peaking too early.

Analysis additionally demonstrates that detrimental break up pacing promotes extra gradual glycogen utilization, preserving vitality reserves for the ultimate phases of the race reasonably than depleting shops early via anaerobic glycolysis.

This psychological pacing suggestions permits higher strategic decision-making when growing tempo within the remaining kilometers.

Implementation Protocol

Your first 5 miles ought to really feel virtually boringly simple.

Place your self with runners 10-15 seconds per mile slower than your aim tempo firstly, resisting the temptation to exit onerous once you’re feeling recent.

The ten-10-10 technique offers a sensible framework: run the primary 10 miles conservatively (10-15 seconds slower than aim tempo), settle into aim tempo for miles 11-20, then push onerous within the remaining 10K for those who’ve fueled and paced appropriately.

This strategy permits you to arrive at mile 20 feeling sturdy reasonably than desperately hanging on, remodeling the ultimate 10K from injury management into a possibility to move runners who began too aggressively.

What This Feels Like

Miles 1-10: Uncomfortably managed, virtually too simple, fixed psychological battle to carry again

Miles 11-16: Settling into rhythm, feeling sturdy, confidence constructing

Miles 16-20: Sustaining tempo feels tougher however manageable, different runners beginning to gradual

Miles 20-26.2: You’re the one doing the passing, legs nonetheless have bounce, in a position to push when it issues

The psychological benefit of passing runners within the remaining 10K reasonably than being handed can’t be overstated—it essentially adjustments your psychological state from survival to competitors.

Technique #4: Educate Your Physique to Run Laborious When Depleted

Most runners do their lengthy runs at a snug, conversational tempo from begin to end.

Whereas this builds cardio base, it fails to organize you for essentially the most essential problem of marathon racing: sustaining tempo when glycogen-depleted and fatigued.

Sadly, conventional lengthy runs at regular tempo don’t create the neuromuscular variations wanted for late-race efficiency.

Analysis on operating economic system adjustments throughout extended train exhibits that fatigue progressively will increase floor contact time and reduces stride frequency, destroying the biomechanical effectivity you want most within the remaining 10K.

The Coaching Resolution

Quick-finish lengthy runs particularly practice your physique to take care of operating economic system and recruit muscle fibers effectively when glycogen-depleted and fatigued.

These exercises train the neuromuscular system to take care of kind and tempo when each intuition screams to decelerate.

Research on operating economic system sturdiness discovered that runners who skilled their skill to withstand fatigue-induced biomechanical adjustments confirmed considerably higher late-race efficiency than those that solely centered on constructing cardio capability.

How one can Construction Quick-End Lengthy Runs

Implement these exercises 6-10 weeks earlier than your aim marathon, utilizing them 2-3 instances throughout your coaching block.

Development #1: 16 miles simple + remaining 3 miles at marathon tempo

Development #2: 18 miles simple + remaining 4 miles at marathon tempo

Development #3: 14 miles simple + remaining 6 miles at half-marathon tempo

The aim isn’t to run all the future quick—that defeats the aim of coaching the depleted state.

You could construct fatigue first, then apply operating at aim tempo (or sooner) when your physique needs to decelerate.

​In the event you’ve executed methods 1-5 appropriately, mile 20 turns into the start of your strongest operating, not the beginning of survival mode.

You’re passing runners as an alternative of being handed, sustaining kind as an alternative of collapsing, pushing tempo as an alternative of hanging on.

The ultimate 10K stops being one thing you endure and turns into your victory lap—the miles the place all of your coaching and strategic preparation compound into the efficiency you’ve labored for.


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